Anti-wrinkle cream
There are many anti-wrinkle creams. The ingredients you used are explained below.

Topical Retinoid
This ingredient has been on the market for a long time and is considered one of the most effective against wrinkles. It is part of almost every anti-aging creams or anti-wrinkle.

Can cause redness, dryness, itching and a burning or tingling sensation. Brands with higher concentrations are known tretinoin (Renova, Retin-A) and Tazarotene (Avage, Tazorac), these require a prescription. In Latin America and Spain are relatively cheap in USA and Canada are quite expensive.

Also found in cosmetic creams for wrinkles. The effectiveness of anti-wrinkle creams depends in part on the concentration of retinol and the mixture of ingredients. Read more about the retinol

Other active ingredients against wrinkles
Other ingredients in anti-wrinkle creams are alpha-hydroxy acids, kinetin (kinetin), coenzyme Q10, peptides, minerals and metals like copper and antioxidants.

These ingredients improve wrinkles and skin condition but the results are light. They have the advantage of not causing as much irritation as does the retinol. Its use is especially recommended for the prevention of wrinkles.

Surgical procedures and other techniques
There are a variety of techniques for skin rejuvenation. Since injections and fillings to surgical procedures or surgeries. Each one works differently and has advantages and disadvantages. Among these are:

Dermabrasion.
This procedure involves brushing the surface layer of the skin to promote the formation of new skin with more collagen.

It’s rough treatment causing redness, swelling and scabs that last a couple of weeks during which you can not work. The redness lasts for months. Gives very good results.